SCHEMBL17427646

SCHEMBL17427646

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)c4ccc6c(ccc7c8ccccc8sc76)c4n5-c4ccc5ccccc5c4)cc3)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 2/20 0.33
PMM2 O15305 1/20 0.33
MPI P34949 1/20 0.33
PHOSPHO1 Q8TCT1 1/20 0.33
HPGD P15428 1/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
MTOR P42345 1/20 0.32
RPA1 P27694 1/20 0.32
MAPK9 P45984 1/20 0.31
MAPK10 P53779 1/20 0.31
NR3C1 P04150 1/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1B1 Q16678 1/20 0.31
PIM3 Q86V86 2/20 0.30
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
ALOX5 P09917 1/20 0.30
PIM1 P11309 1/20 0.30
PIM2 Q9P1W9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17427705 0.97 PMM2 (0.33) PMM2MPIPHOSPHO1HPGDPIK3CD
SCHEMBL17427637 0.95 PIK3CD (0.36) LIMK1PMM2MPIPHOSPHO1PIK3CD
SCHEMBL17427634 0.91 PIK3CD (0.34) LIMK1PMM2MPIPHOSPHO1PIK3CD
SCHEMBL17427643 0.91 LIMK1 (0.33) LIMK1HPGDNR3C1PIM3TNKS
SCHEMBL17427635 0.91 PMM2 (0.37) PMM2MPIPHOSPHO1HPGDPIK3CD
SCHEMBL17427636 0.90 KDM4E (0.33) LIMK1PIK3CDPIK3CAMTORCYP1A1
SCHEMBL15126853 0.89 LIMK1 (0.36) LIMK1HPGDPIK3CANR3C1PIM3
SCHEMBL17427639 0.87 PMM2 (0.32) PMM2MPIPHOSPHO1HPGD
SCHEMBL23862260 0.87 KDM4E (0.34) LIMK1PMM2MPIPHOSPHO1HPGD
SCHEMBL19653735 0.87 KDM4E (0.34) LIMK1PMM2MPIPHOSPHO1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9401484-B2 Organic light-emitting device having increased electron transport ability of an electron transport region SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-26 US disclosed
US-9401484-B2 Organic light-emitting device having increased electron transport ability of an electron transport region SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-26 US disclosed
US-20160013430-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed
US-20160013430-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed