Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25560103 | 0.69 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL19084117 | 0.69 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL19083897 | 0.65 | — | — | |
| SCHEMBL11557901 | 0.63 | ESR1 (0.38) | — | |
| SCHEMBL5591446 | 0.62 | — | — | |
| SCHEMBL28795073 | 0.62 | — | — | |
| SCHEMBL7517135 | 0.62 | — | — | |
| SCHEMBL11137017 | 0.62 | — | — | |
| SCHEMBL1316723 | 0.62 | — | — | |
| SCHEMBL15700676 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166939-B1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH INC (US) | 2019-06-05 | — | — | EP | disclosed |
| WO-2016007534-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2016-01-14 | — | — | WO | disclosed |