⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31137497 | 0.96 | — | — | |
| SCHEMBL1074133 | 0.61 | — | — | |
| SCHEMBL2573967 | 0.61 | — | — | |
| SCHEMBL31049972 | 0.61 | — | — | |
| SCHEMBL2573667 | 0.59 | — | — | |
| SCHEMBL22581275 | 0.57 | — | — | |
| SCHEMBL25187788 | 0.56 | — | — | |
| SCHEMBL14656069 | 0.56 | — | — | |
| SCHEMBL24805836 | 0.56 | — | — | |
| SCHEMBL17793414 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016007534-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2016-01-14 | — | — | WO | disclosed |