⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17417599 | 0.89 | — | — | |
| SCHEMBL17417596 | 0.84 | — | — | |
| SCHEMBL18975234 | 0.80 | — | — | |
| SCHEMBL17417714 | 0.79 | — | — | |
| SCHEMBL17417761 | 0.79 | KCNH2 (0.56) | — | |
| Hydrochloric Acid SCHEMBL17417742 | 0.78 | KCNH2 (0.55) | — | |
| SCHEMBL17417820 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL17417756 | 0.75 | — | — | |
| SCHEMBL18975131 | 0.75 | TSHR (0.44) | — | |
| SCHEMBL17417595 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166561-A1 | QUINUCLIDINE COMPOUNDS FOR MODULATING ALPHA7-NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY | ALPHARMAGEN LLC (US) | 2017-06-15 | — | — | US | disclosed |
| US-9434724-B2 | Quinuclidines for modulating alpha 7 activity | ALPHARMAGEN, LLC (US) | 2016-09-06 | — | — | US | disclosed |
| US-20160009706-A1 | QUINUCLIDINES FOR MODULATING ALPHA 7 ACTIVITY | ALPHARMAGEN, LLC | 2016-01-14 | — | — | US | disclosed |