Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 12/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | TTK | P33981 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | STK3 | Q13188 | 1/20 | 0.38 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682845 | 0.85 | PTK2 (0.49) | PTK2CNR2ATRATRIPMTOR | |
| SCHEMBL1682818 | 0.75 | PTK2 (0.61) | PTK2CSNK2A1 | |
| SCHEMBL17429717 | 0.69 | TTK (0.48) | PTK2TTKATRATRIPCSNK2A1 | |
| SCHEMBL20336327 | 0.68 | PTK2 (0.63) | PTK2CSNK2A1 | |
| SCHEMBL1674012 | 0.68 | PTK2 (0.65) | PTK2CSNK2A1 | |
| SCHEMBL29523133 | 0.68 | PTK2 (0.62) | PTK2CSNK2A1 | |
| SCHEMBL29523377 | 0.68 | PTK2 (0.65) | PTK2CSNK2A1 | |
| SCHEMBL1674147 | 0.68 | PTK2 (0.62) | PTK2CSNK2A1 | |
| SCHEMBL17429716 | 0.68 | PTK2 (0.51) | PTK2TTKPIK3CDPIK3CG | |
| SCHEMBL1682813 | 0.67 | PTK2 (0.64) | PTK2ATRATRIPCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016006921-A1 | ACUTE MYELOID LEUKEMIA TARGETED THERAPEUTIC AGENT WITH REDUCED DRUG SIDE EFFECTS | 한국과학기술연구원 | 2016-01-14 | — | — | WO | disclosed |