Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17431471 | 0.87 | FFAR1 (0.49) | PPARAPPARDPPARGMAPTALDH1A1 | |
| SCHEMBL15212615 | 0.82 | PPARD (0.61) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL17431486 | 0.81 | PPARD (0.46) | PPARAPPARDPPARGMAPTALDH1A1 | |
| SCHEMBL15212601 | 0.80 | PPARD (0.40) | PPARAPPARDPPARGMAPTALDH1A1 | |
| SCHEMBL17431353 | 0.80 | PPARA (0.42) | PPARAPPARDPPARGMAPTALDH1A1 | |
| SCHEMBL15212694 | 0.80 | PPARD (0.48) | PPARAPPARDPPARGMAPTALDH1A1 | |
| SCHEMBL17431420 | 0.78 | PPARD (0.53) | PPARAPPARDPPARGMAPTALDH1A1 | |
| SCHEMBL17431333 | 0.78 | PPARD (0.39) | PPARAPPARDPPARG | |
| SCHEMBL17431456 | 0.78 | PPARD (0.52) | PPARAPPARDPPARGMAPTALDH1A1 | |
| SCHEMBL17431488 | 0.78 | PPARA (0.44) | PPARAPPARDPPARGMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238639-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-19 | — | — | US | disclosed |