Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.74 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800471 | 0.85 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL1742388 | 0.79 | BCL2 (0.65) | BCL2BCL2L1 | |
| SCHEMBL1742180 | 0.78 | BCL2 (0.63) | BCL2BCL2L1 | |
| SCHEMBL1742850 | 0.78 | BCL2 (0.63) | BCL2BCL2L1 | |
| SCHEMBL1958426 | 0.77 | BCL2 (0.73) | BCL2BCL2L1 | |
| SCHEMBL1955301 | 0.77 | BCL2 (0.62) | BCL2BCL2L1 | |
| SCHEMBL1956951 | 0.77 | BCL2 (0.61) | BCL2BCL2L1 | |
| SCHEMBL1955833 | 0.76 | — | — | |
| SCHEMBL2996436 | 0.76 | BCL2 (0.74) | BCL2BCL2L1 | |
| SCHEMBL1957083 | 0.76 | BCL2 (0.61) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387559-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2011-11-23 | — | — | EP | claimed |
| WO-2010083442-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-07-22 | — | — | WO | claimed |