⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1743557 | 0.92 | BCL2 (0.59) | — | |
| SCHEMBL1744624 | 0.90 | BCL2 (0.47) | — | |
| SCHEMBL1744450 | 0.89 | BCL2 (0.48) | — | |
| SCHEMBL19424899 | 0.87 | — | — | |
| SCHEMBL1955108 | 0.86 | BCL2 (0.46) | — | |
| SCHEMBL1954514 | 0.86 | — | — | |
| SCHEMBL19424895 | 0.86 | BCL2 (0.70) | — | |
| SCHEMBL1956538 | 0.85 | BCL2 (0.78) | — | |
| SCHEMBL1955884 | 0.84 | BCL2 (0.65) | — | |
| SCHEMBL19424706 | 0.81 | BCL2 (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511264-B1 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC (US) | 2015-03-11 | — | — | EP | claimed |
| EP-2511264-A1 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | Abbott Laboratories (US) | 2012-10-17 | — | — | EP | claimed |
| US-20100184750-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-07-22 | — | — | US | claimed |
| EP-2511264-B1 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC (US) | 2015-03-11 | — | — | EP | disclosed |
| US-8426422-B2 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC. (US) | 2013-04-23 | — | — | US | disclosed |
| EP-2511264-A1 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | Abbott Laboratories (US) | 2012-10-17 | — | — | EP | disclosed |
| EP-2387560-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8042193-B1 | Systems and methods for controlling data access by use of a universal anonymous identifier | Albright Associates (US) | 2011-10-18 | — | — | US | disclosed |
| US-20100184750-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-07-22 | — | — | US | disclosed |
| WO-2010083441-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-07-22 | — | — | WO | disclosed |