Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17434929 | 0.88 | MELK (0.60) | MELK | |
| SCHEMBL17435003 | 0.87 | MELK (0.75) | MELK | |
| SCHEMBL12504855 | 0.86 | MELK (1.00) | MELK | |
| Hydrochloric Acid SCHEMBL529481 | 0.86 | MELK (0.99) | MELK | |
| SCHEMBL17434975 | 0.78 | MELK (0.79) | MELK | |
| SCHEMBL531023 | 0.78 | MELK (0.90) | MELK | |
| SCHEMBL17434967 | 0.77 | MELK (0.76) | MELK | |
| SCHEMBL17434913 | 0.76 | MELK (0.74) | MELK | |
| SCHEMBL17434864 | 0.76 | MELK (0.77) | MELK | |
| SCHEMBL17434904 | 0.75 | MELK (0.74) | MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2597955-B1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE INC (JP) | 2016-01-20 | — | — | EP | disclosed |