⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35811 | 0.81 | — | — | |
| SCHEMBL20637048 | 0.75 | — | — | |
| SCHEMBL293941 | 0.75 | — | — | |
| SCHEMBL1800908 | 0.75 | TSHR (0.39) | — | |
| SCHEMBL11252202 | 0.75 | — | — | |
| SCHEMBL90117 | 0.73 | — | — | |
| SCHEMBL2956063 | 0.73 | — | — | |
| SCHEMBL5977475 | 0.71 | — | — | |
| SCHEMBL4438002 | 0.71 | — | — | |
| SCHEMBL3316507 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11390604-B2 | Imidazole-pyrazole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2022-07-19 | — | — | US | claimed |
| EP-3934756-A1 | NOVEL IMIDAZOLE-PYRAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2022-01-12 | — | — | EP | claimed |
| CN-113613722-A | Novel imidazole-pyrazole derivatives | 豪夫迈·罗氏有限公司 | 2021-11-05 | — | — | CN | claimed |
| US-20200290998-A1 | NOVEL IMIDAZOLE-PYRAZOLE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2020-09-17 | — | — | US | claimed |
| WO-2020182648-A1 | NOVEL IMIDAZOLE-PYRAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2020-09-17 | — | — | WO | claimed |
| US-11390604-B2 | Imidazole-pyrazole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2022-07-19 | — | — | US | disclosed |
| EP-3934756-A1 | NOVEL IMIDAZOLE-PYRAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2022-01-12 | — | — | EP | disclosed |
| CN-113613722-A | Novel imidazole-pyrazole derivatives | 豪夫迈·罗氏有限公司 | 2021-11-05 | — | — | CN | disclosed |
| US-20200290998-A1 | NOVEL IMIDAZOLE-PYRAZOLE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2020-09-17 | — | — | US | disclosed |
| WO-2020182648-A1 | NOVEL IMIDAZOLE-PYRAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2020-09-17 | — | — | WO | disclosed |
| US-8674006-B2 | Black pigment dispersion | BASF SE Ludwigshafen (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120172498-A1 | BLACK PIGMENT DISPERSION | BASF SE (DE) | 2012-07-05 | — | — | US | disclosed |
| EP-2387599-A1 | BLACK PIGMENT DISPERSION | BASF SE (DE) | 2011-11-23 | — | — | EP | disclosed |
| US-8039718-B2 | Inbred corn line BB33 | Limagrain Europe S.A. (FR) | 2011-10-18 | — | — | US | disclosed |
| WO-2010081756-A1 | BLACK PIGMENT DISPERSION | BASF SE (DE) | 2010-07-22 | — | — | WO | disclosed |