Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1743666 | 0.93 | S1PR1 (0.35) | PIK3CDPIK3CBPIK3CGS1PR1S1PR3 | |
| SCHEMBL1337962 | 0.90 | S1PR1 (0.32) | PIK3CDPIK3CBPIK3CGS1PR1S1PR3 | |
| SCHEMBL1338485 | 0.90 | S1PR1 (0.37) | PIK3CDPIK3CBPIK3CGS1PR1S1PR3 | |
| SCHEMBL1742465 | 0.87 | S1PR1 (0.33) | S1PR1S1PR3 | |
| SCHEMBL1338064 | 0.87 | HDAC4 (0.36) | PIK3CDPIK3CBPIK3CGS1PR1S1PR3 | |
| SCHEMBL1337433 | 0.85 | S1PR1 (0.38) | PIK3CDPIK3CBPIK3CGS1PR1S1PR3 | |
| SCHEMBL1742464 | 0.80 | S1PR1 (0.37) | S1PR1S1PR3TSHR | |
| SCHEMBL13263464 | 0.76 | S1PR1 (0.39) | S1PR1S1PR3 | |
| SCHEMBL1337404 | 0.74 | S1PR1 (0.37) | PIK3CDPIK3CBPIK3CGS1PR1S1PR3 | |
| SCHEMBL1337394 | 0.74 | S1PR1 (0.42) | S1PR1S1PR3HTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387571-A1 | OXADIAZOLE DERIVATIVES AS SLPL RECEPTOR AGONISTS | Almirall S.A. (ES) | 2011-11-23 | — | — | EP | claimed |
| US-8041930-B2 | Data processing apparatus and method for controlling thread access of register sets when selectively operating in secure and non-secure domains | ARM LIMITED (GB) | 2011-10-18 | — | — | US | claimed |
| WO-2010081692-A1 | OXADIAZOLE DERIVATIVES AS SLPL RECEPTOR AGONISTS | ALMIRALL, S.A. (ES) | 2010-07-22 | — | — | WO | claimed |