Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | PDE8B | O95263 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17437518 | 0.83 | RPS6KA5 (0.50) | RPS6KA5ALDH1A1AOC3FGFR1ATM | |
| SCHEMBL17437416 | 0.81 | RPS6KA5 (0.51) | RPS6KA5ALDH1A1FGFR1ATM | |
| SCHEMBL17437574 | 0.81 | RPS6KA5 (0.48) | RPS6KA5ALDH1A1FGFR1ATM | |
| SCHEMBL17437622 | 0.81 | RPS6KA5 (0.49) | RPS6KA5ALDH1A1AOC3CYP2D6CCR5 | |
| SCHEMBL17437510 | 0.80 | RPS6KA5 (0.47) | RPS6KA5ALDH1A1FGFR1ATM | |
| SCHEMBL17437357 | 0.79 | RPS6KA5 (0.46) | RPS6KA5ALDH1A1FGFR1ATM | |
| SCHEMBL17437391 | 0.78 | RPS6KA5 (0.46) | RPS6KA5ALDH1A1FGFR1ATM | |
| SCHEMBL17437326 | 0.77 | RPS6KA5 (0.45) | RPS6KA5ALDH1A1FGFR1ATM | |
| SCHEMBL17437386 | 0.75 | RPS6KA5 (0.49) | RPS6KA5ALDH1A1CYP3A4CYP2C9AOC3 | |
| SCHEMBL17437446 | 0.75 | RPS6KA5 (0.43) | RPS6KA5ALDH1A1FGFR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170050963-A1 | MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-23 | — | — | US | disclosed |
| US-9512120-B2 | Microbicidally active imidazopyridine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-06 | — | — | US | disclosed |
| US-20160016949-A1 | MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050963-A1 | MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES | IDO1, IDO2, FOXM1 | RPS6KA5 2731/4885ALDH1A1 928/4885CYP3A4 59/4885 |
| US-20160016949-A1 | MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES | IDO1, IDO2, FOXM1 | RPS6KA5 2731/4885ALDH1A1 928/4885CYP3A4 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.