Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 11/20 | 0.66 |
| ▸ | RIPK3 | Q9Y572 | 3/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745786 | 0.91 | CSNK1E (0.80) | CSNK1ERIPK3 | |
| SCHEMBL1744710 | 0.89 | CSNK1E (0.66) | CSNK1ERIPK3PIM1 | |
| SCHEMBL1744422 | 0.89 | CSNK1E (0.76) | CSNK1ERIPK3 | |
| SCHEMBL1744537 | 0.88 | CSNK1E (0.67) | CSNK1ERIPK3ACVR1PIM1 | |
| SCHEMBL3107152 | 0.86 | CSNK1E (0.78) | CSNK1ERIPK3PIM1 | |
| SCHEMBL3107143 | 0.86 | CSNK1E (0.78) | CSNK1ERIPK3PIM1 | |
| SCHEMBL477034 | 0.84 | CSNK1E (0.59) | CSNK1EACVR1PIM1 | |
| SCHEMBL477036 | 0.84 | CSNK1E (0.59) | CSNK1EACVR1PIM1 | |
| SCHEMBL1743668 | 0.82 | CSNK1E (0.79) | CSNK1ERIPK3 | |
| SCHEMBL3115839 | 0.81 | CSNK1E (0.78) | CSNK1ERIPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385946-A1 | DERIVATIVES OF 6-CYCLOAMINO-2,3-DI-PYRIDINYL-IMIDAZO[1,2-B]-PYRIDAZINE, PREPARATION AND TUERAPEUTIC APPLICATION THEREOF | SANOFI (FR) | 2011-11-16 | — | — | EP | disclosed |
| US-8040450-B2 | Liquid crystal electro-optic device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010070238-A1 | DERIVATIVES OF 6-CYCLOAMINO-2,3-DI-PYRIDINYL-IMIDAZO[1,2-B]-PYRIDAZINE, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2010-06-24 | — | — | WO | disclosed |