Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 10/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.37 |
| ▸ | PIM1 | P11309 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17440424 | 1.00 | PIM2 (0.37) | PIM2PIM3PIM1 | |
| SCHEMBL17440431 | 0.90 | PIM2 (0.46) | PIM2PIM3PIM1 | |
| SCHEMBL12495335 | 0.87 | PIM1 (0.36) | PIM2PIM3PIM1 | |
| SCHEMBL17440458 | 0.82 | PIM1 (0.43) | PIM2PIM3PIM1 | |
| SCHEMBL17440459 | 0.82 | PIM1 (0.43) | PIM2PIM3PIM1 | |
| SCHEMBL12495231 | 0.78 | PIM1 (0.45) | PIM2PIM3PIM1 | |
| SCHEMBL17440436 | 0.78 | PIM2 (0.38) | PIM2PIM3PIM1 | |
| SCHEMBL12495491 | 0.78 | PIM1 (0.43) | PIM2PIM3PIM1 | |
| SCHEMBL17417434 | 0.76 | PIM2 (0.51) | PIM2PIM3PIM1 | |
| SCHEMBL17417436 | 0.76 | PIM2 (0.51) | PIM2PIM3PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016010897-A1 | BICYCLIC HETEROAROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION (US) | 2016-01-21 | — | — | WO | disclosed |