Phosphine

Phosphine

SCHEMBL1744080

Oc1cc(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1.P

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.62
PDE4B Q07343 3/20 0.53
PDE4A P27815 2/20 0.53
PDE4C Q08493 2/20 0.53
PDE4D Q08499 2/20 0.53
ALOX5 P09917 2/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
BCL2L1 Q07817 1/20 0.48
HSD17B10 Q99714 1/20 0.48
HTT P42858 1/20 0.43
GPR35 Q9HC97 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
ESR2 Q92731 4/20 0.40
ESR1 P03372 3/20 0.40
HSD17B1 P14061 2/20 0.40
HSD17B2 P37059 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21382004 0.98 BACE1 (0.65) BACE1PDE4BPDE4APDE4CPDE4D
SCHEMBL28096487 0.96 BACE1 (0.62) BACE1PDE4BPDE4APDE4CPDE4D
Methane SCHEMBL28838467 0.96 BACE1 (0.62) BACE1PDE4BPDE4APDE4CPDE4D
Ethane SCHEMBL27486393 0.94 BACE1 (0.60) BACE1PDE4BPDE4APDE4CPDE4D
Ethylene SCHEMBL28403381 0.94 BACE1 (0.60) BACE1PDE4BPDE4APDE4CPDE4D
SCHEMBL6521502 0.91 BACE1 (0.61) BACE1PDE4BPDE4APDE4CPDE4D
Tetramethylammonium Ion SCHEMBL28422549 0.90 BACE1 (0.56) BACE1PDE4BPDE4APDE4CPDE4D
SCHEMBL1760415 0.83 PDE4B (0.62) BACE1PDE4BPDE4APDE4CPDE4D
SCHEMBL9236954 0.83 BACE1 (0.62) BACE1PDE4BPDE4APDE4CPDE4D
SCHEMBL27678112 0.82 BACE1 (0.59) BACE1PDE4BPDE4APDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110272451-B Preparation method of tetraphenylphenol phosphonium salt 肯特催化材料股份有限公司 2021-08-17 CN claimed
CN-110272451-A A kind of preparation method of tetraphenyl phenol phosphonium salt 肯特催化材料股份有限公司 2019-09-24 CN claimed
CN-107001609-A The method and makrolon prepared therefrom of catalyst are added in melt polymerization 沙特基础工业全球技术有限公司 2017-08-01 CN claimed
CN-113772882-A Process wastewater treatment method for producing phase transfer catalyst 杭州永邦环保科技有限公司 2021-12-10 CN disclosed
CN-110272451-B Preparation method of tetraphenylphenol phosphonium salt 肯特催化材料股份有限公司 2021-08-17 CN disclosed
CN-110272451-B Preparation method of tetraphenylphenol phosphonium salt 肯特催化材料股份有限公司 2021-08-17 CN disclosed
CN-110272451-B Preparation method of tetraphenylphenol phosphonium salt 肯特催化材料股份有限公司 2021-08-17 CN disclosed
EP-2550322-B1 FLAME RETARDANT COMBINATIONS FOR POLYESTER ELASTOMERS AND FLAME RETARDED EXTRUSION OR MOLDING COMPOSITIONS THEREFROM CLARIANT FINANCE BVI LTD (VG) 2020-06-10 EP disclosed
CN-107207718-B Preparation of highly heat-resistant (co) polycarbonates by the transesterification process 科思创德国股份有限公司 2019-12-03 CN disclosed
CN-110272451-A A kind of preparation method of tetraphenyl phenol phosphonium salt 肯特催化材料股份有限公司 2019-09-24 CN disclosed
CN-110272451-A A kind of preparation method of tetraphenyl phenol phosphonium salt 肯特催化材料股份有限公司 2019-09-24 CN disclosed
US-20110237695-A1 Flame Retardant Combinations For Polyester Elastomers And Flame Retarded Extrusion Or Molding Compositions Therefrom CLARIANT INTERNATIONAL LTD. (CH) 2011-09-29 US disclosed
WO-2011116906-A1 FLAME RETARDANT COMBINATIONS FOR POLYESTER ELASTOMERS AND FLAME RETARDED EXTRUSION OR MOLDING COMPOSITIONS THEREFROM CLARIANT INTERNATIONAL LTD (CH) 2011-09-29 WO disclosed
CN-102153847-A Polycarbonates with improved transmission BAYER MATERIALSCIENCE AG 2011-08-17 CN disclosed
WO-2010080491-A1 FLAME RETARDANT COMBINATIONS FOR POLYESTERS AND FLAME RETARDED POLYESTER MOULDING COMPOSITIONS THEREFROM CLARIANT INTERNATIONAL LTD (CH) 2010-07-15 WO disclosed
US-7645850-B2 Poly(block-phosphonato-ester) and poly(block-phosphonato-carbonate) and methods of making same FRX POLYMERS, INC. (US) 2010-01-12 US disclosed
CN-101506310-A Poly (block-phosphonato-ester) and poly (block-phosphonato-carbonate) and methods for their preparation FRX POLYMERS LLP (US) 2009-08-12 CN disclosed
EP-1919977-A2 POLY (BLOCK-PHOSPHONATO-ESTER) AND POLY (BLOCK-PHOSPHONATO-CARBONATE) AND METHODS OF MAKING SAME FRX Polymers, LLP (US) 2008-05-14 EP disclosed
US-20070129511-A1 Poly(Block-Phosphonato-Ester) And Poly(Block-Phosphonato-Carbonate) And Methods of Making Same FRX POLYMERS, INC. 2007-06-07 US disclosed
WO-2007022008-A2 POLY (BLOCK-PHOSPHONATO-ESTER) AND POLY (BLOCK-PHOSPHONATO-CARBONATE) AND METHODS OF MAKING SAME FRX POLYMERS, LLP (US) 2007-02-22 WO disclosed