SCHEMBL174427

SCHEMBL174427

NCCCCC(N)CNCCN

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
NOS3 P29474 1/20 0.45
NOS1 P29475 1/20 0.45
ANPEP P15144 1/20 0.42
CA12 O43570 5/20 0.41
CA6 P23280 5/20 0.41
CA7 P43166 5/20 0.41
CA9 Q16790 5/20 0.41
CA14 Q9ULX7 5/20 0.41
CA5B Q9Y2D0 5/20 0.41
RECQL P46063 2/20 0.41
CA2 P00918 4/20 0.40
CA4 P22748 4/20 0.40
CA5A P35218 4/20 0.40
CA3 P07451 3/20 0.40
ALOX15 P16050 3/20 0.40
CA1 P00915 2/20 0.40
F13A1 P00488 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL214897 1.00 TDP1 (0.45) TDP1MEN1KMT2ANOS3NOS1
SCHEMBL30435308 0.93 TDP1 (0.46) TDP1MEN1KMT2ANOS3NOS1
SCHEMBL351230 0.91 CA12 (0.48) TDP1MEN1KMT2ANOS3NOS1
SCHEMBL114607 0.91 CA12 (0.48) TDP1MEN1KMT2ANOS3NOS1
SCHEMBL174695 0.91 CA12 (0.48) TDP1MEN1KMT2ANOS3NOS1
SCHEMBL14430423 0.90 GSR (0.39) TDP1MEN1KMT2ANOS3NOS1
SCHEMBL174573 0.89 CA12 (0.58) TDP1MEN1KMT2ANOS3NOS1
SCHEMBL16697214 0.87 CA12 (0.47) TDP1MEN1KMT2ANOS3NOS1
SCHEMBL175639 0.87 CA12 (0.56) TDP1MEN1KMT2ANOS3NOS1
SCHEMBL6862210 0.86 CA12 (0.48) TDP1MEN1KMT2ANOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170145497-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation 2017-05-25 US disclosed
US-9433827-B2 Golf equipment formed from castable formulation with unconventionally low hardness and increased shear resistance ACUSHNET COMPANY (US) 2016-09-06 US disclosed
US-20150072807-A1 GOLF EQUIPMENT FORMED FROM CASTABLE FORMULATION WITH UNCONVENTIONALLY LOW HARDNESS AND INCREASED SHEAR RESISTANCE ACUSHNET COMPANY (US) 2015-03-12 US disclosed
US-8907040-B2 Golf equipment formed from castable formulation with unconventionally low hardness and increased shear resistance ACUSHNET COMPANY (US) 2014-12-09 US disclosed
US-8674051-B2 Polyurea and polyurethane compositions for golf equipment ACUSHNET COMPANY (US) 2014-03-18 US disclosed
EP-2424913-B1 CASTABLE POLYUREA COMPOSITIONS FOR GOLF BALL COVERS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-10-23 EP disclosed
US-8455609-B2 Castable polyurea formulation for golf ball covers ACUSHNET COMPANY (US) 2013-06-04 US disclosed
US-20130137537-A1 GOLF EQUIPMENT FORMED FROM CASTABLE FORMULATION WITH UNCONVENTIONALLY LOW HARDNESS AND INCREASED SHEAR RESISTANCE ACUSHNET COMPANY (US) 2013-05-30 US disclosed
US-8329850-B2 Golf equipment formed from castable formulation with unconventionally low hardness and increased shear resistance ACUSHNET COMPANY (US) 2012-12-11 US disclosed
US-8227565-B2 Polyurethane compositions for golf balls ACUSHNET COMPANY (US) 2012-07-24 US disclosed
EP-0382582-B1 Tetra-aza macrocyles and processes for their preparation CELLTECH LTD (GB) 1995-04-19 EP disclosed
EP-0329737-B1 TRI-AZA MACROCYCLES AND METAL COMPLEXES THEREOF CELLTECH THERAPEUTICS LTD (GB) 1995-04-12 EP disclosed
US-5342936-A Tetra-aza macrocycles and processes for their preparation PARKER DAVID 1994-08-30 US disclosed
US-5247075-A Imaging agents, cytotoxic agents CELLTECH LIMITED (GB) 1993-09-21 US disclosed
WO-1990009388-A1 TETRA-AZA MACROCYCLES AND PROCESSES FOR THEIR PREPARATION CELLTECH LIMITED (GB) 1990-08-23 WO disclosed
EP-0382582-A1 Tetra-aza macrocyles and processes for their preparation CELLTECH THERAPEUTICS LIMITED (GB) 1990-08-16 EP disclosed
EP-0329737-A1 TRI-AZA MACROCYCLES AND METAL COMPLEXES THEREOF CELLTECH THERAPEUTICS LIMITED (GB) 1989-08-30 EP disclosed
EP-0328589-A1 TETRA-AZA MACROCYCLES AND METAL COMPLEXES THEREOF CELLTECH THERAPEUTICS LIMITED (GB) 1989-08-23 EP disclosed
WO-1989001475-A1 TRI-AZA MACROCYCLES AND METAL COMPLEXES THEREOF CELLTECH LIMITED (GB) 1989-02-23 WO disclosed
WO-1989001476-A1 TETRA-AZA MACROCYCLES AND METAL COMPLEXES THEREOF CELLTECH LIMITED (GB) 1989-02-23 WO disclosed