Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 6/20 | 0.73 |
| ▸ | CDK2 | P24941 | 3/20 | 0.65 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.65 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.65 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.65 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.65 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17450185 | 0.90 | CDK1 (0.58) | CDK1CDK2CCNA2CCNA1KDM4E | |
| SCHEMBL17443002 | 0.89 | CDK1 (0.58) | CDK1CDK2CCNA2CCNA1KDM4E | |
| SCHEMBL17450191 | 0.88 | CDK1 (0.57) | CDK1CDK2CCNA2CCNA1KDM4E | |
| SCHEMBL17450190 | 0.87 | CDK1 (0.62) | CDK1CDK2CCNA2CCNA1KDM4E | |
| SCHEMBL17450113 | 0.87 | CDK1 (0.56) | CDK1CDK2CCNA2CCNA1KDM4E | |
| SCHEMBL17442991 | 0.87 | CDK1 (0.56) | CDK1CDK2CCNA2CCNA1KDM4E | |
| SCHEMBL17450195 | 0.87 | CDK1 (0.56) | CDK1CDK2CCNA2CCNA1KDM4E | |
| SCHEMBL17450150 | 0.86 | CDK1 (0.61) | CDK1CDK2CCNA2CCNA1KDM4E | |
| SCHEMBL17442981 | 0.86 | CDK1 (0.58) | CDK1CDK2CCNA2CCNA1KDM4E | |
| SCHEMBL17450188 | 0.85 | CCNE1 (0.75) | CDK1CDK2TDP1CCNE2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10519160-B2 | Imaging agents for neural flux | THE GENERAL HOSPITAL CORPORATION (US) | 2019-12-31 | — | — | US | disclosed |
| US-10519160-B2 | Imaging agents for neural flux | THE GENERAL HOSPITAL CORPORATION (US) | 2019-12-31 | — | — | US | disclosed |
| US-20180258090-A1 | IMAGING AGENTS FOR NEURAL FLUX | UNITED STATES DEPARTMENT OF ENERGY | 2018-09-13 | — | — | US | disclosed |
| WO-2016011394-A1 | IMAGING AGENTS FOR NEURAL FLUX | THE GENERAL HOSPITAL CORPORATION (US) | 2016-01-21 | — | — | WO | disclosed |
| WO-2016011394-A1 | IMAGING AGENTS FOR NEURAL FLUX | THE GENERAL HOSPITAL CORPORATION (US) | 2016-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10519160-B2 | Imaging agents for neural flux | SLC18A2, SLC18A3, PMP22 | CDK1 2522/4885CDK2 3061/4885CCNA2 3113/4885 |
| US-20180258090-A1 | IMAGING AGENTS FOR NEURAL FLUX | SLC18A2, SLC18A3, PMP22 | CDK1 2522/4885CDK2 3061/4885CCNA2 3113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.