Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17440139 | 0.91 | TP53 (0.45) | TP53NPC1NR2F2RAB9AENPP3 | |
| SCHEMBL17440066 | 0.88 | TP53 (0.47) | TP53NPC1NR2F2RAB9AENPP3 | |
| SCHEMBL17450461 | 0.87 | CHRM1 (0.45) | TP53ENPP3GRM2PARP1ENPP1 | |
| SCHEMBL17440146 | 0.80 | CHRM1 (0.51) | CHRM1 | |
| SCHEMBL17440096 | 0.78 | CHRM1 (0.65) | CHRM1 | |
| SCHEMBL17440117 | 0.78 | CHRM1 (0.65) | CHRM1 | |
| SCHEMBL17440138 | 0.78 | CHRM1 (0.44) | TP53ENPP3ENPP1CHRM1POLB | |
| SCHEMBL17443029 | 0.74 | PARP1 (0.43) | TP53NPC1ENPP3PARP1ENPP1 | |
| SCHEMBL17443022 | 0.73 | PARP1 (0.45) | TP53NPC1ENPP3PARP1ENPP1 | |
| SCHEMBL17443099 | 0.71 | CHRM1 (0.42) | ENPP3PARP1ENPP1CHRM1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016009297-A1 | PYRIDINE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | PFIZER INC. (US) | 2016-01-21 | — | — | WO | disclosed |