Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 19/20 | 0.82 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17440071 | 0.89 | CHRM1 (0.98) | CHRM1 | |
| SCHEMBL17439995 | 0.89 | CHRM1 (0.98) | CHRM1 | |
| SCHEMBL17439996 | 0.89 | CHRM1 (0.98) | CHRM1 | |
| SCHEMBL17439994 | 0.89 | CHRM1 (0.98) | CHRM1 | |
| SCHEMBL17440070 | 0.89 | CHRM1 (0.98) | CHRM1 | |
| SCHEMBL18756540 | 0.89 | CHRM1 (0.98) | CHRM1 | |
| SCHEMBL17440025 | 0.88 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL17440125 | 0.88 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL18725485 | 0.88 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL18725406 | 0.86 | CHRM1 (0.89) | CHRM1PDE2APDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016009297-A1 | PYRIDINE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | PFIZER INC. (US) | 2016-01-21 | — | — | WO | disclosed |