Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 9/20 | 0.66 |
| ▸ | LATS1 | O95835 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | RIPK3 | Q9Y572 | 4/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3115650 | 0.94 | CSNK1E (0.73) | CSNK1ELATS1 | |
| SCHEMBL1744357 | 0.89 | CSNK1E (0.55) | CSNK1ELATS1PIM1PRKCQPRKD1 | |
| SCHEMBL1744576 | 0.82 | CSNK1E (0.92) | CSNK1ELATS1RIPK3 | |
| SCHEMBL3116616 | 0.80 | CSNK1E (0.51) | CSNK1ERIPK3 | |
| SCHEMBL3116817 | 0.79 | CSNK1E (1.00) | CSNK1ELATS1RIPK3 | |
| SCHEMBL3107141 | 0.79 | CSNK1E (1.00) | CSNK1ELATS1RIPK3 | |
| SCHEMBL1744366 | 0.78 | LATS1 (0.50) | CSNK1ELATS1PIM1PRKCQPRKD1 | |
| SCHEMBL3112096 | 0.78 | CSNK1E (0.52) | CSNK1E | |
| SCHEMBL1746568 | 0.78 | CSNK1E (0.77) | CSNK1ELATS1RIPK3 | |
| SCHEMBL3110570 | 0.77 | CSNK1E (1.00) | CSNK1ELATS1RIPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385946-A1 | DERIVATIVES OF 6-CYCLOAMINO-2,3-DI-PYRIDINYL-IMIDAZO[1,2-B]-PYRIDAZINE, PREPARATION AND TUERAPEUTIC APPLICATION THEREOF | SANOFI (FR) | 2011-11-16 | — | — | EP | disclosed |
| US-8040450-B2 | Liquid crystal electro-optic device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010070238-A1 | DERIVATIVES OF 6-CYCLOAMINO-2,3-DI-PYRIDINYL-IMIDAZO[1,2-B]-PYRIDAZINE, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010070238-A1 | DERIVATIVES OF 6-CYCLOAMINO-2,3-DI-PYRIDINYL-IMIDAZO[1,2-B]-PYRIDAZINE, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2010-06-24 | — | — | WO | disclosed |