SCHEMBL1744520

SCHEMBL1744520

Cc1cc(N2C=C(c3cnc(N(C)C)c4c3CCC(C)(C)C4)ON2)cc(C)c1CC(O)CO

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 3/20 0.32
S1PR3 Q99500 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1338513 0.78 S1PR1 (0.44) S1PR1S1PR3
SCHEMBL1338331 0.66 S1PR1 (0.45) S1PR1S1PR3
SCHEMBL1338665 0.65 S1PR1 (0.46) S1PR1S1PR3
SCHEMBL1338338 0.62 S1PR1 (0.38) S1PR1S1PR3
SCHEMBL2472250 0.59 S1PR1 (0.45) S1PR1S1PR3
SCHEMBL13254714 0.59 S1PR1 (0.42) S1PR1S1PR3
SCHEMBL2462578 0.58 S1PR1 (0.42) S1PR1S1PR3
SCHEMBL1336405 0.57 HPGD (0.37)
SCHEMBL1854429 0.55 S1PR1 (0.79) S1PR1S1PR3
SCHEMBL1858622 0.54 S1PR1 (0.55) S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2387571-A1 OXADIAZOLE DERIVATIVES AS SLPL RECEPTOR AGONISTS Almirall S.A. (ES) 2011-11-23 EP disclosed
US-8041930-B2 Data processing apparatus and method for controlling thread access of register sets when selectively operating in secure and non-secure domains ARM LIMITED (GB) 2011-10-18 US disclosed
WO-2010081692-A1 OXADIAZOLE DERIVATIVES AS SLPL RECEPTOR AGONISTS ALMIRALL, S.A. (ES) 2010-07-22 WO disclosed