SCHEMBL17445262

SCHEMBL17445262

CCOCCCCNC(CC(C)C)C1(c2ccc(Cl)c(Cl)c2)CCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 20/20 1.00
SLC6A2 P23975 19/20 1.00
SLC6A3 Q01959 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15422073 1.00 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3
SCHEMBL15422663 1.00 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3
SCHEMBL15422266 0.93 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3
SCHEMBL15422510 0.92 SLC6A4 (0.85) SLC6A4SLC6A2SLC6A3
SCHEMBL15422348 0.90 SLC6A4 (0.92) SLC6A4SLC6A2SLC6A3
SCHEMBL15422265 0.90 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3
SCHEMBL15422275 0.90 SLC6A4 (0.92) SLC6A4SLC6A2SLC6A3
SCHEMBL15422775 0.90 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3
SCHEMBL15422779 0.89 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3
SCHEMBL15422677 0.89 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797870-B1 COMPOSITIONS, SYNTHESIS, AND METHODS OF USING 1-[1-PHENYL-CYCLOBUTYL]ISOBUTYLAMINE DERIVATIVES REVIVA PHARMACEUTICALS INC (US) 2019-02-20 EP disclosed
US-9238625-B2 Compositions, synthesis, and methods of using phenylcycloalkylmethylamine derivatives REVIVA PHARMACEUTICALS, INC. (US) 2016-01-19 US disclosed