Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 5/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | BLM | P54132 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7697396 | 0.95 | PRMT1 (0.56) | PRMT1PRMT5CARM1MAPTHPGD | |
| Water SCHEMBL7697398 | 0.95 | PRMT1 (0.56) | PRMT1PRMT5CARM1MAPTHPGD | |
| Water SCHEMBL30750821 | 0.92 | PRMT1 (0.53) | PRMT1PRMT5CARM1MAPTHPGD | |
| SCHEMBL5694877 | 0.90 | MAPT (0.47) | PRMT1PRMT5CARM1MAPTHPGD | |
| SCHEMBL5694876 | 0.90 | MAPT (0.47) | PRMT1PRMT5CARM1MAPTHPGD | |
| SCHEMBL19770612 | 0.89 | PRMT1 (0.48) | PRMT1PRMT5CARM1MAPTHPGD | |
| SCHEMBL13109097 | 0.88 | PRMT1 (0.46) | PRMT1PRMT5CARM1MAPTHPGD | |
| SCHEMBL14450213 | 0.87 | MAPT (0.44) | PRMT1PRMT5CARM1MAPTHPGD | |
| SCHEMBL5084505 | 0.85 | MAPT (0.44) | PRMT1PRMT5CARM1MAPTHPGD | |
| SCHEMBL10036136 | 0.85 | MAPT (0.45) | PRMT1PRMT5CARM1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10041937-B2 | Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent | CANON KABUSHIKI KAISHA (JP) | 2018-08-07 | — | — | US | disclosed |
| US-20160018389-A1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CANON KABUSHIKI KAISHA (JP) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10041937-B2 | Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent | CD68, MSR1, MYADM | PRMT1 3048/4885PRMT5 2680/4885CARM1 2102/4885 |
| US-20160018389-A1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CD68, MSR1, MYADM | PRMT1 3048/4885PRMT5 2680/4885CARM1 2102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.