Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CDK4 | P11802 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14978759 | 0.87 | HTT (0.61) | HTTHIF1ACA12CA1CA2 | |
| SCHEMBL6259021 | 0.83 | CA12 (0.61) | HTTCA12CA1CA2CA9 | |
| SCHEMBL10313438 | 0.81 | HTT (0.65) | HTTHIF1AARKDM4EALDH1A1 | |
| SCHEMBL22745399 | 0.81 | HTT (0.65) | HTTHIF1AARKDM4EALDH1A1 | |
| SCHEMBL14085644 | 0.79 | HIF1A (0.97) | HTTHIF1AARKDM4EALDH1A1 | |
| SCHEMBL24046837 | 0.77 | HTT (0.60) | HTTHIF1AARKDM4EALDH1A1 | |
| SCHEMBL17828237 | 0.77 | HIF1A (0.72) | HTTHIF1AARKDM4EALDH1A1 | |
| SCHEMBL11316310 | 0.77 | HIF1A (0.82) | HTTHIF1AARKDM4EALDH1A1 | |
| SCHEMBL13963728 | 0.76 | HTT (0.58) | HTTHIF1AARKDM4EALDH1A1 | |
| SCHEMBL12135524 | 0.76 | HTT (0.58) | HTTHIF1AARKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9496170-B2 | Interconnect having air gaps and polymer wrapped conductive lines | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2016-11-15 | — | — | US | disclosed |
| US-20160172232-A1 | Interconnect Having Air Gaps and Polymer Wrapped Conductive Lines | TAIWAN SEMICONDUCTOR MFG (TW) | 2016-06-16 | — | — | US | disclosed |
| US-9269668-B2 | Interconnect having air gaps and polymer wrapped conductive lines | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2016-02-23 | — | — | US | disclosed |
| US-20160020176-A1 | INTERCONNECT HAVING AIR GAPS AND POLYMER WRAPPED CONDUCTIVE LINES | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2016-01-21 | — | — | US | disclosed |