Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.60 |
| ▸ | PPARA | Q07869 | 10/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382021 | 0.84 | SMN1; SMN2 (0.59) | PPARGPPARAPTGESALOX5PLA2G4B | |
| SCHEMBL5830137 | 0.83 | PPARA (0.76) | PPARGPPARA | |
| SCHEMBL11046248 | 0.83 | TP53 (0.60) | PPARGPPARAPLA2G4B | |
| SCHEMBL28886753 | 0.82 | PPARA (0.72) | PPARGPPARA | |
| SCHEMBL28381180 | 0.82 | PPARA (0.72) | PPARGPPARA | |
| SCHEMBL28381512 | 0.82 | PPARA (0.72) | PPARGPPARA | |
| SCHEMBL6064663 | 0.80 | PPARA (0.58) | PPARGPPARA | |
| SCHEMBL4818098 | 0.80 | PPARG (0.70) | PPARGPPARA | |
| SCHEMBL295888 | 0.79 | SMN1; SMN2 (0.64) | PPARGPPARA | |
| SCHEMBL4651839 | 0.79 | SMN1; SMN2 (0.64) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |