Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.61 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465995 | 0.87 | MAOB (0.65) | MAOBPDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL8001650 | 0.86 | MAOB (0.71) | MAOBPDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL2202317 | 0.84 | MAOB (0.66) | MAOBPDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL5647010 | 0.83 | MAOB (0.61) | MAOBPDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL4156881 | 0.83 | MAOB (0.61) | MAOBPDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL4538765 | 0.83 | MAOB (0.61) | MAOBPDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL2204650 | 0.83 | MAOB (0.65) | MAOBPDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL1040763 | 0.82 | MAOB (0.80) | MAOBHPGDS | |
| SCHEMBL430324 | 0.81 | MGAM (0.59) | MAOBNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL25302023 | 0.81 | MAOB (0.59) | MAOBPDGFRBPDGFRANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016011209-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2016-01-21 | — | — | WO | disclosed |