Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.57 |
| ▸ | MAP4K1 | Q92918 | 18/20 | 0.57 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442797 | 0.91 | KLKB1 (0.69) | KLKB1MAP4K1 | |
| SCHEMBL21657344 | 0.82 | KLKB1 (0.61) | KLKB1MAP4K1KLK1 | |
| SCHEMBL17447275 | 0.82 | KLKB1 (0.68) | KLKB1MAP4K1 | |
| SCHEMBL17442766 | 0.82 | KLKB1 (0.61) | KLKB1MAP4K1KLK1 | |
| SCHEMBL17442662 | 0.78 | KLKB1 (0.62) | KLKB1MAP4K1KLK1 | |
| SCHEMBL17446986 | 0.78 | KLKB1 (0.60) | KLKB1MAP4K1 | |
| SCHEMBL17909751 | 0.77 | KLKB1 (0.65) | KLKB1MAP4K1 | |
| SCHEMBL17447315 | 0.77 | KLKB1 (0.53) | KLKB1MAP4K1KLK1 | |
| SCHEMBL18370788 | 0.76 | KLKB1 (0.59) | KLKB1MAP4K1 | |
| SCHEMBL17442519 | 0.76 | KLKB1 (0.63) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016011209-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2016-01-21 | — | — | WO | disclosed |