Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 11/20 | 0.54 |
| ▸ | RIPK3 | Q9Y572 | 8/20 | 0.54 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112816 | 0.89 | RIPK3 (0.64) | CSNK1ERIPK3HASPIN | |
| SCHEMBL3121095 | 0.88 | CSNK1E (0.66) | CSNK1ERIPK3HASPINCSNK1D | |
| SCHEMBL1746104 | 0.88 | RIPK3 (0.61) | CSNK1ERIPK3HASPIN | |
| SCHEMBL3115204 | 0.88 | CSNK1E (0.58) | CSNK1ERIPK3HASPINCSNK1D | |
| SCHEMBL1744609 | 0.86 | RIPK3 (0.58) | CSNK1ERIPK3HASPIN | |
| SCHEMBL3113454 | 0.85 | RIPK3 (0.57) | CSNK1ERIPK3HASPINCSNK1D | |
| SCHEMBL1745981 | 0.85 | RIPK3 (0.59) | CSNK1ERIPK3HASPIN | |
| SCHEMBL3359816 | 0.83 | CSNK1E (0.52) | CSNK1ERIPK3HASPINCSNK1D | |
| SCHEMBL1746048 | 0.80 | RIPK3 (0.53) | CSNK1ERIPK3HASPIN | |
| SCHEMBL3354700 | 0.80 | RIPK3 (0.52) | CSNK1ERIPK3HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385946-A1 | DERIVATIVES OF 6-CYCLOAMINO-2,3-DI-PYRIDINYL-IMIDAZO[1,2-B]-PYRIDAZINE, PREPARATION AND TUERAPEUTIC APPLICATION THEREOF | SANOFI (FR) | 2011-11-16 | — | — | EP | disclosed |
| US-8040450-B2 | Liquid crystal electro-optic device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010070238-A1 | DERIVATIVES OF 6-CYCLOAMINO-2,3-DI-PYRIDINYL-IMIDAZO[1,2-B]-PYRIDAZINE, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2010-06-24 | — | — | WO | disclosed |