Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898230 | 0.87 | ALK (0.78) | ALK | |
| SCHEMBL29962891 | 0.87 | ALK (0.78) | ALK | |
| SCHEMBL20366611 | 0.77 | ALK (0.63) | ALK | |
| SCHEMBL898316 | 0.77 | ALK (0.93) | ALK | |
| SCHEMBL29962364 | 0.77 | ALK (0.93) | ALK | |
| SCHEMBL7807270 | 0.76 | ALK (0.80) | ALK | |
| SCHEMBL897705 | 0.75 | ALK (1.00) | ALK | |
| SCHEMBL897706 | 0.75 | ALK (1.00) | ALK | |
| SCHEMBL7802133 | 0.74 | ALK (0.72) | ALK | |
| SCHEMBL16775686 | 0.73 | ALK (0.72) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-A1 | TETRACYCLIC COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-01-20 | — | — | EP | disclosed |