Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17449399 | 1.00 | IRAK4 (0.90) | IRAK4 | |
| SCHEMBL17440802 | 0.95 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL17442025 | 0.95 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL17441802 | 0.95 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL19130729 | 0.90 | IRAK4 (0.82) | IRAK4 | |
| SCHEMBL17449381 | 0.89 | IRAK4 (0.87) | IRAK4 | |
| SCHEMBL17449434 | 0.89 | IRAK4 (0.87) | IRAK4 | |
| SCHEMBL17449461 | 0.86 | IRAK4 (0.84) | IRAK4 | |
| SCHEMBL17449460 | 0.86 | IRAK4 (0.84) | IRAK4 | |
| SCHEMBL21264130 | 0.85 | IRAK4 (0.82) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016011390-A1 | IRAK4 INHIBITING AGENTS | BIOGEN MA INC. (US) | 2016-01-21 | — | — | WO | disclosed |