Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 18/20 | 0.75 |
| ▸ | PDE2A | O00408 | 1/20 | 0.75 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.75 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17440044 | 1.00 | CHRM1 (0.75) | CHRM1PDE2APDE11APDCD1CD274 | |
| SCHEMBL17440001 | 0.87 | CHRM1 (0.73) | CHRM1PDE2APDE11A | |
| SCHEMBL17440023 | 0.87 | CHRM1 (0.73) | CHRM1PDE2APDE11A | |
| SCHEMBL17443104 | 0.87 | CHRM1 (0.73) | CHRM1PDE2APDE11A | |
| SCHEMBL17443102 | 0.87 | CHRM1 (0.73) | CHRM1PDE2APDE11A | |
| SCHEMBL17443124 | 0.86 | CHRM1 (1.00) | CHRM1PDE2APDE11A | |
| SCHEMBL17440028 | 0.86 | CHRM1 (1.00) | CHRM1PDE2APDE11A | |
| SCHEMBL17440029 | 0.86 | CHRM1 (1.00) | CHRM1PDE2APDE11A | |
| SCHEMBL31659435 | 0.86 | CHRM1 (1.00) | CHRM1PDE2APDE11A | |
| SCHEMBL17443122 | 0.86 | CHRM1 (1.00) | CHRM1PDE2APDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160016907-A1 | PYRIDINE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | PFIZER INC. (US) | 2016-01-21 | — | — | US | disclosed |
| US-20160016907-A1 | PYRIDINE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | PFIZER INC. (US) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016907-A1 | PYRIDINE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | CHRM1, CHRM2, CHRM4 | CHRM1 1/4885PDE2A 818/4885PDE11A 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.