Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 11/20 | 0.72 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.72 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.72 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.72 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | CDK1 | P06493 | 16/20 | 0.67 |
| ▸ | CDK5 | Q00535 | 9/20 | 0.67 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.65 |
| ▸ | CLK2 | P49760 | 1/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.65 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.65 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.65 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.64 |
| ▸ | CDK7 | P50613 | 6/20 | 0.64 |
| ▸ | CCNH | P51946 | 5/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004030 | 0.82 | CDK1 (0.80) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL17004020 | 0.82 | CDK1 (0.80) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL17004017 | 0.81 | CDK2 (0.85) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL2097192 | 0.80 | CDK1 (1.00) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL1216848 | 0.80 | CDK1 (1.00) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL1214567 | 0.80 | CDK1 (1.00) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL30848443 | 0.80 | CCNE2 (0.73) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL30848442 | 0.80 | CCNE2 (0.73) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL3082573 | 0.79 | CDK1 (1.00) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| Ethane SCHEMBL1218446 | 0.79 | CDK2 (0.86) | CDK2CCNE1CCNE2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10519160-B2 | Imaging agents for neural flux | THE GENERAL HOSPITAL CORPORATION (US) | 2019-12-31 | — | — | US | disclosed |
| WO-2016011394-A1 | IMAGING AGENTS FOR NEURAL FLUX | THE GENERAL HOSPITAL CORPORATION (US) | 2016-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10519160-B2 | Imaging agents for neural flux | SLC18A2, SLC18A3, PMP22 | CDK2 3061/4885CCNE1 3918/4885CCNE2 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.