Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 3/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12185042 | 0.97 | HDAC3 (0.48) | HDAC3HDAC6NCOR2CA12CA1 | |
| SCHEMBL15216675 | 0.92 | HDAC3 (0.48) | HDAC3HDAC6NCOR2CA12CA1 | |
| SCHEMBL15218369 | 0.91 | CA1 (0.50) | CA12CA1CA2CA9CA14 | |
| SCHEMBL12185011 | 0.89 | HDAC3 (0.37) | HDAC3HDAC6NCOR2CA12CA1 | |
| SCHEMBL15216685 | 0.88 | HDAC3 (0.48) | HDAC3HDAC6NCOR2CA12CA1 | |
| SCHEMBL17955395 | 0.86 | CA1 (0.49) | CA12CA1CA2CA9CA14 | |
| SCHEMBL15218283 | 0.84 | CA1 (0.50) | CA12CA1CA2CA9CA14 | |
| SCHEMBL15218363 | 0.84 | CA1 (0.50) | CA12CA1CA2CA9CA14 | |
| SCHEMBL17122479 | 0.81 | CA1 (0.43) | CA12CA1CA2CA9CA14 | |
| SCHEMBL15216676 | 0.79 | CA1 (0.51) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975409-A1 | ZANAMIVIR PHOSPHONATE CONGENERS WITH ANTI-INFLUENZA ACTIVITY AND DETERMINING OSELTAMIVIR SUSCEPTIBILITY OF INFLUENZA VIRUSES | Academia Sinica (TW) | 2016-01-20 | — | — | EP | disclosed |