Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 4/20 | 0.81 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744369 | 0.89 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL1956747 | 0.84 | BCL2 (0.80) | BCL2BCL2L1 | |
| SCHEMBL1956281 | 0.83 | BCL2 (0.77) | BCL2BCL2L1 | |
| SCHEMBL1957709 | 0.82 | BCL2 (0.79) | BCL2BCL2L1 | |
| SCHEMBL1955710 | 0.82 | BCL2 (0.60) | BCL2BCL2L1 | |
| SCHEMBL1957833 | 0.82 | BCL2 (0.78) | BCL2BCL2L1 | |
| SCHEMBL1955935 | 0.81 | BCL2 (0.63) | BCL2 | |
| SCHEMBL1743443 | 0.81 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL1957158 | 0.80 | BCL2 (0.78) | BCL2 | |
| SCHEMBL18240011 | 0.78 | BCL2 (0.79) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387559-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2011-11-23 | — | — | EP | claimed |
| WO-2010083442-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-07-22 | — | — | WO | claimed |