SCHEMBL1745568

SCHEMBL1745568

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nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.40
AKR1B1 P15121 1/20 0.32
TSHR P16473 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6771973 1.00 MPI (0.40) MPIAKR1B1TSHRTDP1ALDH1A1
Phosphoric Acid SCHEMBL5792557 0.91 MPI (0.48) MPI
SCHEMBL16600269 0.85 MPI (0.33) MPI
SCHEMBL17984946 0.82 MPI (0.39) MPIAKR1B1
SCHEMBL17984945 0.77 MPI (0.39) MPIAKR1B1TSHRTDP1ALDH1A1
SCHEMBL6436950 0.76 TSHR (0.33) TSHRTDP1ALDH1A1
SCHEMBL16600605 0.75 MPI (0.38) MPIALDH1A1
SCHEMBL9842949 0.74 TSHR (0.32) TSHRTDP1ALDH1A1
SCHEMBL29876881 0.73 TSHR (0.47) TSHRTDP1ALDH1A1
SCHEMBL16600199 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170281772-A1 A NEURAL SUBSTRATE FOR SUGAR PREFERENCE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2017-10-05 US claimed
US-12351847-B2 Methods for the improved formation of acarbose UNIVERSITÄT BIELEFELD (DE) 2025-07-08 US disclosed
CN-114555811-B Methods for improving acarbose formation 拜耳公司 2025-03-25 CN disclosed
US-20240110216-A1 Production of Activated TDP-Deoxysugars in Recombinant Microorganisms ZUCHEM INC (US) 2024-04-04 US disclosed
US-11773423-B2 Production of activated TDP-deoxysugars in recombinant microorganisms ZUCHEM INC (US) 2023-10-03 US disclosed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-20230227879-A1 METHODS FOR THE IMPROVED FORMATION OF ACARBOSE UNIVERSITÄT BIELEFELD (DE) 2023-07-20 US disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
EP-3647430-B1 MICROBIAL PRODUCTION OF FATTY AMINES GENOMATICA INC (US) 2022-10-26 EP disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-20080182801-A1 Core 2 glcnac-t inhibitors BTG INTERNATIONAL LIMITED (GB) 2008-07-31 US disclosed
EP-1919486-A2 CORE 2 GLCNAC-T INHIBITORS BTG INTERNATIONAL LIMITED (GB) 2008-05-14 EP disclosed
EP-1909802-A2 STEROIDAL GLYCOSIDE COMPOUNDS AS CORE 2 GLCNAC-T INHIBITORS BTG International Limited (GB) 2008-04-16 EP disclosed
WO-2007104576-A1 MEDICAMENT COMPRISING N-ACETYLMANNOSAMINE OR DERIVATIVES THEREOF AND ITS USE MOSETTER, KURT (CH) 2007-09-20 WO disclosed
WO-2007035897-A2 IMPROVED LIVE ATTENUATED VACCINE STRAIN FOR PREVENTION OF TULAREMIA PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-03-29 WO disclosed
US-20070010461-A1 Core 2 GlcNAc-T inhibitors BTG INTERNATIONAL LIMITED (GB) 2007-01-11 US disclosed
WO-2007003948-A2 CORE 2 GLCNAC-T INHIBITORS BTG INTERNATIONAL LIMITED (GB) 2007-01-11 WO disclosed
WO-2007003957-A2 STEROIDAL GLYCOSIDE COMPOUNDS AS CORE 2 GLCNAC- T INHIBITORS BTG INTERNATIONAL LIMITED (GB) 2007-01-11 WO disclosed
US-20070010462-A1 Core 2 GlcNAc-T inhibitors III BTG INTERNATIONAL LIMITED (GB) 2007-01-11 US disclosed
US-H1817-H Enzymatic methods for the preparation of pradimicins BRISTOL-MYERS SQUIBB COMPANY (US) 1999-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010461-A1 Core 2 GlcNAc-T inhibitors MAN2A1, CSGALNACT1, MAN2B1 MPI 105/4885AKR1B1 704/4885TSHR 1377/4885
US-20070010462-A1 Core 2 GlcNAc-T inhibitors III CSGALNACT1, ENGASE, GALNT6 MPI 384/4885AKR1B1 421/4885TSHR 265/4885
US-20080182801-A1 Core 2 glcnac-t inhibitors CSGALNACT1, ENGASE, GALNT6 MPI 543/4885AKR1B1 413/4885TSHR 305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.