Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 11/20 | 0.92 |
| ▸ | RIPK3 | Q9Y572 | 7/20 | 0.53 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118856 | 0.96 | CSNK1E (1.00) | CSNK1ERIPK3DYRK3CCNT1CDK9 | |
| SCHEMBL3119337 | 0.94 | CSNK1E (1.00) | CSNK1ERIPK3 | |
| SCHEMBL3119317 | 0.91 | CSNK1E (0.77) | CSNK1ERIPK3DYRK3CCNT1CDK9 | |
| SCHEMBL3729274 | 0.91 | CSNK1E (0.77) | CSNK1ERIPK3DYRK3CCNT1CDK9 | |
| SCHEMBL17976955 | 0.90 | CSNK1E (0.93) | CSNK1ERIPK3 | |
| SCHEMBL3106595 | 0.89 | CSNK1E (0.91) | CSNK1ERIPK3 | |
| SCHEMBL3116053 | 0.88 | CSNK1E (0.79) | CSNK1ERIPK3DYRK3CCNT1CDK9 | |
| SCHEMBL3725856 | 0.88 | CSNK1E (0.75) | CSNK1ERIPK3DYRK3CCNT1CDK9 | |
| SCHEMBL477099 | 0.88 | CSNK1E (0.72) | CSNK1ERIPK3DYRK3CCNT1CDK9 | |
| SCHEMBL3114292 | 0.87 | CSNK1E (0.83) | CSNK1ERIPK3HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385946-A1 | DERIVATIVES OF 6-CYCLOAMINO-2,3-DI-PYRIDINYL-IMIDAZO[1,2-B]-PYRIDAZINE, PREPARATION AND TUERAPEUTIC APPLICATION THEREOF | SANOFI (FR) | 2011-11-16 | — | — | EP | disclosed |
| US-8040450-B2 | Liquid crystal electro-optic device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010070238-A1 | DERIVATIVES OF 6-CYCLOAMINO-2,3-DI-PYRIDINYL-IMIDAZO[1,2-B]-PYRIDAZINE, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2010-06-24 | — | — | WO | disclosed |