Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14632150 | 0.94 | ELANE (0.49) | ELANECYP2C9CYP3A4 | |
| SCHEMBL1744774 | 0.89 | ELANE (0.50) | ELANECYP2C9CYP3A4 | |
| SCHEMBL14632020 | 0.83 | ELANE (0.57) | ELANECYP2C9CYP3A4 | |
| SCHEMBL15456716 | 0.82 | ELANE (0.56) | ELANECYP2C9CYP3A4 | |
| SCHEMBL15456137 | 0.81 | ELANE (0.54) | ELANECYP2C9CYP3A4 | |
| SCHEMBL14632156 | 0.79 | ELANE (0.57) | ELANECYP2C9CYP3A4 | |
| SCHEMBL231395 | 0.79 | ELANE (0.53) | ELANECYP2C9CYP3A4 | |
| SCHEMBL230751 | 0.79 | ELANE (0.54) | ELANECYP2C9CYP3A4 | |
| SCHEMBL230760 | 0.79 | ELANE (0.58) | ELANECYP2C9CYP3A4 | |
| SCHEMBL15456718 | 0.78 | ELANE (0.64) | ELANECYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385945-B1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | BAYER IP GMBH (DE) | 2013-01-23 | — | — | EP | disclosed |
| EP-2385945-A1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | Bayer Pharma Aktiengesellschaft (DE) | 2011-11-16 | — | — | EP | disclosed |
| US-8041896-B2 | Virtualization platform with dedicated cache access | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010078953-A1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-07-15 | — | — | WO | disclosed |