Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 13/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | STAT5A | P42229 | 1/20 | 0.41 |
| ▸ | STAT5B | P51692 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17968865 | 1.00 | ACE (0.46) | ACEACE2TSHRPRCPSTAT6 | |
| SCHEMBL17968867 | 1.00 | ACE (0.46) | ACEACE2TSHRPRCPSTAT6 | |
| SCHEMBL19465507 | 1.00 | ACE (0.46) | ACEACE2TSHRPRCPSTAT6 | |
| SCHEMBL17834576 | 0.93 | ACE (0.49) | ACEACE2TSHRPRCP | |
| SCHEMBL15037081 | 0.92 | ACE (0.46) | ACEACE2TSHRPRCP | |
| SCHEMBL15037086 | 0.92 | ACE (0.46) | ACEACE2TSHRPRCP | |
| SCHEMBL17459612 | 0.91 | ACE (0.46) | ACEACE2TSHRPRCPSTAT6 | |
| SCHEMBL17459610 | 0.91 | ACE (0.46) | ACEACE2TSHRPRCPSTAT6 | |
| SCHEMBL19465512 | 0.91 | ACE (0.46) | ACEACE2TSHRPRCPSTAT6 | |
| SCHEMBL17459609 | 0.91 | ACE (0.46) | ACEACE2TSHRPRCPSTAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | Receptos, Inc. (US) | 2017-05-31 | — | — | EP | disclosed |
| WO-2016015014-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2016-01-28 | — | — | WO | disclosed |