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SCHEMBL17460853

SCHEMBL17460853

C=C(C)C(=O)OCCCC[Si]1(C)O[Si](C)(CCCOC(=O)C(=C)C)O[Si](C)(CCCOC(=O)C(=C)C)O[Si](C)(CCCOC(=O)C(=C)C)O1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.54
▸ THRB P10828 1/20 0.43
▸ POLB P06746 1/20 0.42
▸ APEX1 P27695 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15682455 1.00 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL526560 0.97 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4917872 0.97 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28045531 0.90 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9764025 0.90 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9764053 0.90 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2368508 0.90 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15369485 0.90 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2367990 0.90 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9763990 0.90 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9243007-B2 Organopolysiloxane, method for producing the same, and curable resin composition containing the organopolysiloxane ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-01-26 — — US disclosed