Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 11/20 | 0.81 |
| ▸ | MAX | P61244 | 7/20 | 0.81 |
| ▸ | MEN1 | O00255 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16107836 | 0.90 | MYC (1.00) | MYCMAXMEN1KMT2AIDO1 | |
| SCHEMBL31053963 | 0.90 | MYC (1.00) | MYCMAXMEN1KMT2AIDO1 | |
| SCHEMBL16107519 | 0.88 | MYC (1.00) | MYCMAXMEN1KMT2AIDO1 | |
| SCHEMBL16139694 | 0.85 | MYC (0.69) | MYCMAXMEN1KMT2AIDO1 | |
| SCHEMBL16142058 | 0.81 | MYC (0.72) | MYCMAXMEN1KMT2AIDO1 | |
| SCHEMBL16141994 | 0.81 | MYC (0.82) | MYCMAXMEN1KMT2AIDO1 | |
| SCHEMBL16107898 | 0.80 | MYC (0.82) | MYCMAXMEN1KMT2AIDO1 | |
| SCHEMBL16139677 | 0.79 | MYC (0.81) | MYCMAXMEN1KMT2AIDO1 | |
| SCHEMBL16139687 | 0.78 | MYC (0.80) | MYCMAXMEN1KMT2AIDO1 | |
| SCHEMBL6831367 | 0.78 | MEN1 (0.78) | MYCMAXMEN1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242944-B2 | Potent analogues of the C-Myc inhibitor 10074-G5 with improved cell permeability | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2016-01-26 | — | — | US | disclosed |