Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 8/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099559 | 0.86 | HPGD (0.57) | HPGDKDM4EHTTMAPTLMNA | |
| SCHEMBL29411029 | 0.84 | KDM4E (0.61) | HPGDKDM4EHTTMAPTLMNA | |
| SCHEMBL28326868 | 0.84 | KDM4E (0.61) | HPGDKDM4EHTTMAPTLMNA | |
| SCHEMBL17461866 | 0.84 | NPC1 (0.64) | HPGDKDM4EHTTMAPTLMNA | |
| SCHEMBL17461833 | 0.80 | NPC1 (0.59) | HPGDKDM4EHTTMAPTLMNA | |
| SCHEMBL17461825 | 0.80 | HPGD (0.53) | HPGDKDM4EHTTMAPTLMNA | |
| SCHEMBL17461839 | 0.80 | HPGD (0.53) | HPGDKDM4EHTTMAPTLMNA | |
| SCHEMBL17461867 | 0.78 | HPGD (0.51) | HPGDKDM4EHTTMAPTLMNA | |
| SCHEMBL17461844 | 0.78 | NPSR1 (0.56) | HPGDKDM4EHTTMAPTLMNA | |
| SCHEMBL13264839 | 0.77 | KDM4E (0.53) | HPGDKDM4EHTTMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | AR, KLK3, BRDT | HPGD 166/4885KDM4E 1549/4885HTT 3094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.