SCHEMBL17463566

SCHEMBL17463566

Nc1ccc([C@H](N)Cc2ccccc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.52
MAOB P27338 4/20 0.50
MAOA P21397 3/20 0.50
CYP2D6 P10635 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
SLC6A2 P23975 2/20 0.48
TAAR1 Q96RJ0 2/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
SIGMAR1 Q99720 1/20 0.48
CYP2A6 P11509 1/20 0.48
ADORA2A P29274 1/20 0.48
ADORA1 P30542 1/20 0.48
ANPEP P15144 1/20 0.45
CNR2 P34972 1/20 0.45
PRKACA P17612 1/20 0.44
PRKACG P22612 1/20 0.44
PRKACB P22694 1/20 0.44
AKT2 P31751 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9323047 1.00 EPHX1 (0.52) EPHX1MAOBMAOACYP2D6CYP1A2
SCHEMBL9322166 0.92 MAOB (0.50) EPHX1MAOBMAOACYP2D6CYP1A2
Hydrochloric Acid SCHEMBL15392583 0.90 MAOB (0.52) EPHX1MAOBMAOACYP2D6CYP1A2
Hydrochloric Acid SCHEMBL15392584 0.90 MAOB (0.52) EPHX1MAOBMAOACYP2D6CYP1A2
SCHEMBL3451169 0.87 EPHX1 (0.61) EPHX1MAOACYP2D6CYP1A2CYP2C19
SCHEMBL468022 0.87 EPHX1 (0.61) EPHX1MAOACYP2D6CYP1A2CYP2C19
SCHEMBL272604 0.87 EPHX1 (0.61) EPHX1MAOACYP2D6CYP1A2CYP2C19
Hydrochloric Acid SCHEMBL28839661 0.85 EPHX1 (0.58) EPHX1MAOACYP2D6CYP1A2CYP2C19
SCHEMBL10842083 0.83 SLC6A2 (0.55) EPHX1MAOBMAOASLC6A2TAAR1
SCHEMBL3282010 0.82 SLC6A2 (0.52) EPHX1MAOACYP2D6CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016013875-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-01-28 WO disclosed