Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | KCNQ3 | O43525 | 5/20 | 0.61 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.61 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17784128 | 0.85 | NPC1 (0.57) | NPC1RAB9AKCNQ3KCNQ2MAOB | |
| SCHEMBL25485683 | 0.84 | KMT2A (0.56) | NPC1RAB9A | |
| SCHEMBL19479148 | 0.83 | KCNQ3 (0.50) | NPC1RAB9AKCNQ3KCNQ2MAOB | |
| SCHEMBL17803501 | 0.83 | KCNQ3 (0.50) | NPC1RAB9AKCNQ3KCNQ2MAOB | |
| SCHEMBL17465706 | 0.83 | NPC1 (0.62) | NPC1RAB9AKCNQ3KCNQ2MAOB | |
| SCHEMBL8361564 | 0.82 | NPC1 (0.68) | NPC1RAB9AKCNQ3KCNQ2MAOB | |
| SCHEMBL10192542 | 0.82 | MEN1 (0.53) | — | |
| SCHEMBL20577784 | 0.82 | HDAC1 (0.52) | NPC1RAB9AKCNQ3KCNQ2LMNA | |
| SCHEMBL17936108 | 0.82 | KIT (0.50) | NPC1RAB9AKCNQ3KCNQ2MAOB | |
| SCHEMBL15847328 | 0.81 | NPC1 (0.64) | NPC1RAB9AKCNQ3KCNQ2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938236-B2 | Antiviral agents against HBV infection | DREXEL UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |
| US-20160024004-A1 | NOVEL ANTIVIRAL AGENTS AGAINST HBV INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024004-A1 | NOVEL ANTIVIRAL AGENTS AGAINST HBV INFECTION | HAVCR2, EIF2AK2, NR1H4 | NPC1 272/4885RAB9A 3576/4885KCNQ3 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.