⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4504815 | 0.75 | — | — | |
| SCHEMBL72400 | 0.73 | — | — | |
| SCHEMBL3870589 | 0.70 | — | — | |
| SCHEMBL14830653 | 0.69 | — | — | |
| SCHEMBL14830503 | 0.69 | — | — | |
| SCHEMBL867457 | 0.69 | — | — | |
| SCHEMBL14829308 | 0.69 | — | — | |
| SCHEMBL7569561 | 0.66 | — | — | |
| SCHEMBL7409317 | 0.66 | — | — | |
| SCHEMBL336074 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285640-A | Naphthalene dione pyrazine fused ring compound and preparation method and application thereof | 西京学院 | 2025-01-10 | — | — | CN | claimed |
| EP-4204413-B1 | DIHYDROQUINAZOLIN-2-ONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS USEFUL IN THE TREATMENT OF HIV | MERCK SHARP & DOHME LLC (US) | 2024-09-25 | — | — | EP | claimed |
| CN-116745269-A | Dihydroquinazolin-2-one derivatives as selective cytotoxic agents for the treatment of HIV | 默沙东有限责任公司 | 2023-09-12 | — | — | CN | claimed |
| CN-114920930-A | Pyrazine-benzoquinone structure-containing polymer and application thereof in lithium ion/water-based zinc ion battery | 安徽大学 | 2022-08-19 | — | — | CN | claimed |
| CN-107686483-B | Heptacyclic acetals, their preparation, antithrombotic activity and use | 首都医科大学 | 2020-01-14 | — | — | CN | claimed |
| EP-2174934-B1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2012-06-06 | — | — | EP | claimed |
| JP-2002539162-A | — | — | 2002-11-19 | — | — | JP | claimed |
| EP-1161238-A1 | AMYOTROPIC LATERAL SCLEROSIS TREATMENT WITH A COMBINATION OF RILUZOLE AND AN AMPA RECEPTOR ANTAGONIST | Aventis Pharma S.A. (FR) | 2001-12-12 | — | — | EP | claimed |
| WO-2000054772-A1 | AMYOTROPIC LATERAL SCLEROSIS TREATMENT WITH A COMBINATION OF RILUZOLE AND AN AMPA RECEPTOR ANTAGONIST | AVENTIS PHARMA S.A. (FR) | 2000-09-21 | — | — | WO | claimed |
| EP-4574207-A2 | MEANS AND METHODS FOR TREATING COPPER-RELATED DISEASES | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2025-06-25 | — | — | EP | disclosed |
| CN-119859151-A | Alkaloid compound separated from rhizoma smilacis glabrae and preparation method and application thereof | 北京振东光明药物研究院有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-119409834-A | Methods and compositions for promoting and enhancing T cell mediated immune responses through ADCC targeting of CD39 expressing cells | 北京恩瑞尼生物科技股份有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119285640-A | Naphthalene dione pyrazine fused ring compound and preparation method and application thereof | 西京学院 | 2025-01-10 | — | — | CN | disclosed |
| WO-2024192335-A1 | ALTERNATIVE STRATEGIES FOR METHANOBACTIN PRODUCTION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-09-19 | — | — | WO | disclosed |
| EP-0927171-A1 | PYRAZINONES AND TRIAZINONES AND THEIR DERIVATIVES THEREOF | Du Pont Pharmaceuticals Company (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011075-A1 | PYRAZINONES AND TRIAZINONES AND THEIR DERIVATIVES THEREOF | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-03-19 | — | — | WO | disclosed |
| EP-0457817-A1 | OXODIAMINOCYCLOTRIPHOSPHAZENE COMPOUNDS, THEIR PREPARATION AND THEIR APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1991-11-27 | — | — | EP | disclosed |
| WO-1991008212-A1 | MONO-BINO AND DI-BINO OXODIAMINODICYCLOPHOSPHAZENE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1991-06-13 | — | — | WO | disclosed |
| EP-0402096-A2 | Anticonvulsant pyrazines | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-12-12 | — | — | EP | disclosed |
| WO-1990009390-A1 | OXODIAMINOCYCLOTRIPHOSPHAZENE COMPOUNDS, THEIR PREPARATION AND THEIR APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1990-08-23 | — | — | WO | disclosed |