⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782028 | 0.67 | — | — | |
| SCHEMBL7045502 | 0.67 | — | — | |
| SCHEMBL10279027 | 0.63 | — | — | |
| SCHEMBL13836590 | 0.62 | — | — | |
| SCHEMBL2517257 | 0.62 | — | — | |
| SCHEMBL12777837 | 0.62 | — | — | |
| SCHEMBL12956727 | 0.60 | BRD4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL752660 | 0.60 | — | — | |
| SCHEMBL745819 | 0.59 | BRD4 (0.32) | — | |
| SCHEMBL1023500 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310755-B1 | A NOVEL PROCESS FOR THE PREPARATION OF TERIFLUNOMIDE | BIOCON LTD (IN) | 2021-02-24 | — | — | EP | claimed |
| EP-1817036-B1 | MODULATORS OF MUSCARINIC RECEPTORS | VERTEX PHARMA (US) | 2012-07-04 | — | — | EP | claimed |
| EP-1817036-A2 | MODULATORS OF MUSCARINIC RECEPTORS | Vertex Pharmaceuticals Incorporated (US) | 2007-08-15 | — | — | EP | claimed |
| US-20060270653-A1 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED | 2006-11-30 | — | — | US | claimed |
| WO-2006058303-A2 | MODULATORS OF MUSCARINIC RECEPTORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2006-06-01 | — | — | WO | claimed |
| US-6660858-B2 | Made by reacting a benzoxazole with a leaving group at the 2 position and a diamine of given formula | LION BIOSCIENCE AG (DE) | 2003-12-09 | — | — | US | claimed |
| US-20020161028-A1 | 2-aminobenzoxazole derivatives and combinatorial libraries thereof | LION BIOSCIENCE, AG (DE) | 2002-10-31 | — | — | US | claimed |
| WO-2002079753-A2 | 2-AMINOBENZOXAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2002-10-10 | — | — | WO | claimed |
| EP-3310755-B1 | A NOVEL PROCESS FOR THE PREPARATION OF TERIFLUNOMIDE | BIOCON LTD (IN) | 2021-02-24 | — | — | EP | disclosed |
| EP-3310755-A1 | A NOVEL PROCESS FOR THE PREPARATION OF TERIFLUNOMIDE | Biocon Limited (IN) | 2018-04-25 | — | — | EP | disclosed |
| EP-3310755-A1 | A NOVEL PROCESS FOR THE PREPARATION OF TERIFLUNOMIDE | Biocon Limited (IN) | 2018-04-25 | — | — | EP | disclosed |
| WO-2016203410-A1 | A NOVEL PROCESS FOR THE PREPARATION OF TERIFLUNOMIDE | BIOCON LIMITED (IN) | 2016-12-22 | — | — | WO | disclosed |
| WO-2016203410-A1 | A NOVEL PROCESS FOR THE PREPARATION OF TERIFLUNOMIDE | BIOCON LIMITED (IN) | 2016-12-22 | — | — | WO | disclosed |
| EP-2785708-B1 | INSECTICIDAL TRIAZINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-23 | — | — | EP | disclosed |
| EP-1310488-A1 | FUSED BICYCLIC AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-20020161028-A1 | 2-aminobenzoxazole derivatives and combinatorial libraries thereof | LION BIOSCIENCE, AG (DE) | 2002-10-31 | — | — | US | disclosed |
| WO-2002079753-A2 | 2-AMINOBENZOXAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2002-10-10 | — | — | WO | disclosed |
| WO-2002051806-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2002-07-04 | — | — | WO | disclosed |
| EP-1176140-A1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2002-01-30 | — | — | EP | disclosed |
| EP-0016277-A1 | 2-Carbonyl-3-hydroxy-alkenonitriles, their use as anti-arthritic agents and processes for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-10-01 | — | — | EP | disclosed |