SCHEMBL1747700

SCHEMBL1747700

C1=CC=C2NC=CC=C2N=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2502650 0.71
SCHEMBL28166931 0.65
SCHEMBL2046911 0.64
SCHEMBL8922295 0.64
SCHEMBL2049064 0.64
Hydrochloric Acid SCHEMBL28176836 0.63
SCHEMBL7376330 0.60
SCHEMBL27696131 0.60 MAPT (0.40)
SCHEMBL927156 0.59
SCHEMBL2504107 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2336315-B1 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION AS (DK) 2017-07-19 EP claimed
EP-2336315-A2 Enzymatic encoding methods for efficient synthesis of large libraries Nuevolution A/S (DK) 2011-06-22 EP claimed
US-20070123510-A1 Guanidine derivatives ACTELION PHARMACEUTICALS LTD. (CH) 2007-05-31 US claimed
WO-2025051216-A1 CYP11A1 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF 深圳众格生物科技有限公司 2025-03-13 WO disclosed
CN-118239926-A TLR7 and 8 inhibitors, preparation method and application thereof 上海深势唯思科技有限责任公司 2024-06-25 CN disclosed
CN-118239959-A Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof 上海深势唯思科技有限责任公司 2024-06-25 CN disclosed
US-11702652-B2 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION A/S (DK) 2023-07-18 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-20220257781-A1 POLYMER CONJUGATE BONDED TO TERTIARY AMINE COMPOUND OR IMINE COMPOUND AND PRODUCTION METHOD THEREFOR SEIKAGAKU CORPORATION (JP) 2022-08-18 US disclosed
US-11253517-B2 Small molecule regulators of steroid receptor coactivators and methods of use thereof BAYLOR COLLEGE OF MEDICINE (US) 2022-02-22 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-1096925-A2 USE OF INHIBITORS OF PRENYLTRANSFERASES FOR FOR INHIBITING FUNGAL GROWTH MITOTIX, INC. (US) 2001-05-09 EP disclosed
WO-2000047236-A1 MATRICES FOR DRUG DELIVERY AND METHODS FOR MAKING AND USING THE SAME BIOSTREAM, INC. (US) 2000-08-17 WO disclosed
WO-2000003743-A9 USE OF INHIBITORS OF PRENYLTRANSFERASES FOR INHIBITING FUNGAL GROWTH MITOTIX INC (US) 2000-07-27 WO disclosed
WO-2000003743-A2 USE OF INHIBITORS OF PRENYLTRANSFERASES FOR INHIBITING FUNGAL GROWTH MITOTIX, INC. (US) 2000-01-27 WO disclosed
US-5776902-A Boronophenyl analogs of phospholyrosines TRUSTEES OF TUFTS UNIVERSITY (US) 1998-07-07 US disclosed
US-5580979-A Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions TRUSTEES OF TUFTS UNIVERSITY (US) 1996-12-03 US disclosed
EP-0675887-A1 ANTIALLERGIC TRIAZOLOBENZAZEPINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1995-10-11 EP disclosed
WO-1995025118-A2 INHIBITORS OF SH2 DOMAIN INTERACTIONS TRUSTEES OF TUFTS UNIVERSITY (US) 1995-09-21 WO disclosed
WO-1994013671-A1 ANTIALLERGIC TRIAZOLOBENZAZEPINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1994-06-23 WO disclosed