Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17485531 | 1.00 | GRM2 (0.70) | GRM2KCNH2 | |
| SCHEMBL17484590 | 0.91 | GRM2 (0.67) | GRM2KCNH2 | |
| SCHEMBL20752607 | 0.91 | GRM2 (0.67) | GRM2KCNH2 | |
| SCHEMBL26989597 | 0.90 | GRM2 (0.59) | GRM2KCNH2 | |
| SCHEMBL26987941 | 0.90 | GRM2 (0.59) | GRM2KCNH2 | |
| SCHEMBL17477897 | 0.90 | GRM2 (0.67) | GRM2KCNH2 | |
| SCHEMBL17485466 | 0.89 | GRM2 (0.64) | GRM2KCNH2 | |
| SCHEMBL17485440 | 0.89 | GRM2 (0.64) | GRM2KCNH2 | |
| SCHEMBL18457882 | 0.89 | GRM2 (0.64) | GRM2KCNH2 | |
| SCHEMBL17484566 | 0.87 | GRM2 (0.62) | GRM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008909-A1 | INHIBITORS OF CORONAVIRUS | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-11 | — | — | WO | disclosed |
| WO-2024008909-A1 | INHIBITORS OF CORONAVIRUS | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-11 | — | — | WO | disclosed |
| EP-3177623-A1 | 6,7-DIHYDROPYRAZOLO[1,5-a]PYRAZIN-4(5H)-ONE COMPOUNDS AND THEIR USE AS NEGATIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS | Janssen Pharmaceutica, N.V. (BE) | 2017-06-14 | — | — | EP | disclosed |
| WO-2017018475-A1 | CONDENSED PYRAZOLE DERIVATIVE HAVING NEW LINKER SITE AND MEDICINAL USE OF SAME | 大日本住友製薬株式会社 | 2017-02-02 | — | — | WO | disclosed |
| WO-2016016380-A1 | 6,7-DIHYDROPYRAZOLO[1,5-α]PYRAZIN-4(5H)-ONE COMPOUNDS AND THEIR USE AS NEGATIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-02-04 | — | — | WO | disclosed |