Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 17/20 | 0.69 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12274111 | 0.91 | QPCT (0.71) | QPCTQPCTL | |
| SCHEMBL12274017 | 0.91 | QPCT (0.69) | QPCTQPCTL | |
| SCHEMBL12274886 | 0.91 | QPCT (0.71) | QPCTQPCTL | |
| SCHEMBL12274695 | 0.90 | QPCT (0.68) | QPCTQPCTL | |
| SCHEMBL12275356 | 0.90 | QPCT (0.68) | QPCTQPCTL | |
| SCHEMBL12274316 | 0.89 | QPCT (0.86) | QPCTQPCTL | |
| SCHEMBL12273882 | 0.88 | QPCT (0.66) | QPCTQPCTLFLT3 | |
| SCHEMBL12274174 | 0.88 | QPCT (0.66) | QPCTQPCTL | |
| SCHEMBL12274258 | 0.85 | QPCT (0.60) | QPCTQPCTL | |
| SCHEMBL12274554 | 0.85 | QPCT (0.61) | QPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2686313-B1 | BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2016-02-03 | — | — | EP | disclosed |