Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 12/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12274884 | 0.85 | QPCT (0.61) | QPCTPIK3CDPIK3CAPIK3CBSYK | |
| SCHEMBL12274609 | 0.84 | QPCT (0.65) | QPCTPIK3CDPIK3CAPIK3CBADORA3 | |
| SCHEMBL12274090 | 0.82 | QPCT (0.88) | QPCTPIK3CDPIK3CAPIK3CBSYK | |
| SCHEMBL12274087 | 0.81 | QPCT (0.80) | QPCTPIK3CDPIK3CAPIK3CBMAP3K11 | |
| SCHEMBL12274785 | 0.80 | QPCT (0.65) | QPCTPIK3CDPIK3CAPIK3CBSYK | |
| SCHEMBL12274111 | 0.78 | QPCT (0.71) | QPCTPIK3CDPIK3CAPIK3CBMAP3K11 | |
| SCHEMBL12273938 | 0.78 | QPCT (0.61) | QPCTPIK3CDPIK3CAPIK3CBSYK | |
| SCHEMBL12456210 | 0.78 | QPCT (0.61) | QPCTPIK3CDPIK3CAPIK3CBMAP3K11 | |
| SCHEMBL12274712 | 0.77 | QPCT (0.74) | QPCTPIK3CDPIK3CAPIK3CBSYK | |
| SCHEMBL12274190 | 0.77 | QPCT (0.73) | QPCTPIK3CDPIK3CAPIK3CBMAP3K11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2686313-B1 | BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2016-02-03 | — | — | EP | disclosed |