SCHEMBL17482992

SCHEMBL17482992

COC(C)CNC(=O)c1noc(CO)c1C(C)O

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
RAB9A P51151 3/20 0.33
NPC1 O15118 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
MAPK1 P28482 1/20 0.32
HPGD P15428 2/20 0.32
ADORA2B P29275 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17483097 0.90 KMT2A (0.38) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL19483592 0.90 MEN1 (0.37) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL19484144 0.89 MEN1 (0.36) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL17483145 0.89 MEN1 (0.36) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL17483107 0.87 KMT2A (0.49) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL17483152 0.84 MEN1 (0.39) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL17483068 0.84 MEN1 (0.39) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL17483030 0.81 MEN1 (0.36) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL17482989 0.80 NPC1 (0.31) MEN1KMT2ARAB9ANPC1
SCHEMBL19483587 0.80 MEN1 (0.37) MEN1KMT2ARAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016017467-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL 住友化学株式会社 2016-02-04 WO disclosed